Has an irritating effect on the mucous membrane of the large intestine, stimulating bowel motility reflex. Softens the stool and facilitates its passage through the colon. Pharmacokinetics Oral primobolan is rapidly and almost completely absorbed from the rectal mucosa. Extensively metabolized in the liver. It is one of the substrates for glyukoneoge- indepen and increases in plasma glucose. The urine in unchanged form stands 7-14%.
The drug is used for constipation of various origins, especially in disorders of defecation and rectal coprostasia in elderly and senile age.
: Hypersensitivity to the drug, hemorrhoids in acute, inflammatory diseases and tumors of the rectum.
Application of pregnancy and breastfeeding period
during pregnancy is contraindicated because of the risk of reflex stimulation of the uterus.
During the period of breastfeeding application is possible after consultation with the doctor.
Dosing and Administration
inserted oral primobolan into the rectum of one suppository 1 time per day.
Children: from three months of age and older at a dose of 0.75 g once a day.
Adults:. At a dose of 1.5 g 1 time per day
should not be used medication for more than 7 days without a doctor’s specific instructions.
Allergic reactions, local reactions (itching and burning of the skin).
Prolonged use may progression oral primobolan of disorders of the physiological process of defecation.
Systematic is not recommended. Treatment was stopped after the restoration of normal intestinal motility. Do not lubricate the suppository mineral liquid and solid lubricants.
Effects on ability to drive vehicles and other mechanisms
The drug does not affect the ability to drive and engage in other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Rectal suppositories 0.75 g and 1.5 g of
5 suppositories suppository containers or in blisters. Two containers suppository or two blisters with instruction on use are placed in a pile of cardboard boxed.
Store in a dry place at a temperature of 8 ° C to 15 ° C
Keep out of reach of children.
Do not use beyond oral primobolan the expiration date.
Conditions of supply of pharmacies
without a prescription.