Primobolan acetate high. It penetrates through the blood-tissue barriers (including the blood-brain barrier), cell membranes and subcellular membrane primobolan acetate structures. It accumulates in nervous and muscular tissue, liver and kidney. Report the news – 4-7% in an unmodified form.In adults glutamic acid is administered in combination therapy in the treatment of epilepsy mostly small seizures to equivalents; somatogenic, involution, substance-induced psychosis, reactive states with primobolan acetate symptoms of depression, exhaustion.In the complex therapy of mental retardation in children, Down’s syndrome, cerebral palsy; polio (acute and recovery periods); in progressive myopathy (in combination with pahikarpin hydroiodide or glycine) for the removal and prevention of the neurotoxic effects caused by drugs – isonicotinic acid hydrazide derivatives.
: Hypersensitivity to the drug, a feverish syndrome, hepatic and / or renal failure, peptic ulcer and 12 duodenal ulcers, anemia, leucopenia, irritability, rapidly occurring psychotic reactions, nephrotic syndrome, inhibition of bone marrow hematopoiesis, obesity, children under 3 years.
Pregnancy and lactation
There are no adequate and primobolan acetate well-controlled clinical studies safety of the drug during pregnancy has not been. The application is shown only when the intended benefits to the mother outweighs the potential risk to the fetus.
During treatment it is necessary to resolve the issue of termination of breastfeeding.
Dosing and Administration
The drug is prescribed orally 15-20 minutes before a meal.
Adults take a single dose of 1 g 2-3 times a day.
Children aged 3-4 years – 0.25 g, 5-6 years – 0, 5 g, 7-9 years – 0.5-1 g, aged 10 years and older – 1 g 2-3 times a day.
The course of treatment from 1-2 to 6-12 months.
are possible allergic reactions, nausea, vomiting, abdominal pain, diarrhea, irritability.
With prolonged use – decrease in hemoglobin and development of leukopenia, irritation of the oral mucosa, cracked lips.
Overdose of glutamic acid may be accompanied by abdominal pain, nausea, vomiting. First aid is gastric lavage, activated charcoal. If necessary – symptomatic therapy.
Interaction with other drugs
in combination with thiamine, and pyridoxine drug used for the prevention and treatment of neurotoxic effects caused by drugs group isonicotinic acid hydrazide (isoniazid, ftivazid et al.). When myopathies and muscular dystrophies drug more effective in combination with pahikarpin hydroiodide or glycine.
During treatment should regularly primobolan acetate conduct general clinical blood and urine tests.
With the development of dyspeptic symptoms take medication during or after a meal.
tablets, enteric-coated tablets, 250 mg. 10 tablets in blisters.
2 or 4 blisters with instruction on use are placed in a stack of cardboard.
Allowed blisters along with an equal number of instructions for use are placed in boxes made of corrugated cardboard.
In a dry place at temperatures no higher than 25 ° C. Keep out of the reach of children.