08/19/2016

primobolan for sale

pharmachologic effect

Oral hypoglycemic agents from the group . Primobolan for sale enhances muscle glucose utilization, delay the absorption of carbohydrates in the intestine, inhibits gluconeogenesis in the liver, and improves the sensitivity of tissues to insulin.

The drug reduces the triglyceride and cholesterol in blood plasma, reduces appetite.

Pharmacokinetics

The absorption of the drug from the gastrointestinal tract is 48-52%. The half-life of 9 to 12 hours. Excreted unchanged in the urine.

Indications

  • type II diabetes, in case of failure of sulfonylurea;
  • diabetes mellitus type I (as an adjunct to insulin)

dosage

At the beginning of treatment prescribed medication at a dose of 250-500 mg 1 time / day in the morning. Subsequently, if necessary, the dose is gradually increased to 500-750 mg 2-3 times / day. The maintenance dose is usually 250-500 mg 2-3 times / day.

Primobolan for sale taken orally during or immediately after a meal.

Side effect

Probably: a metallic taste in the mouth, loss of appetite, nausea, allergic reactions, the symptoms of lactic acidosis.

Contraindications

  • diabetic coma, ketoacidosis, lactic acidosis, or a reference to it in history;
  • expressed human liver and / or kidney problems;
  • cardiac and / or respiratory failure;
  • the acute phase of myocardial infarction;
  • extensive surgery and trauma;
  • infectious diseases;
  • pregnancy;
  • lactation (breastfeeding);
  • Hypersensitivity to the biguanide

special instructions

Not recommended the appointment Primobolan for salea in acute infections, exacerbation of chronic infectious and inflammatory diseases, trauma, acute surgical diseases, the danger of dehydration. The drug is not used prior to surgery and for 2 days after the elections. Do not be prescribed to patients older than 60 years, performing heavy physical work, which is associated with an increased risk of lactic acidosis.Primobolan for sale lowers blood glucose only in patients with diabetes, and does not show this action in healthy individuals.

Long-term use of the drug can lead to malabsorption of vitamin B12.

In the event of adverse reactions it is recommended to reduce the dose or temporarily suspend it. With long-term use of the drug is necessary to monitor liver function and the patient’s kidneys.

Drug interactions

The combined application Primobolan for salea with sulfonylureas, insulin, salicylates, MAO inhibitors, ACE inhibitors, clofibrate derivatives arises potentiation of its hypoglycemic action.

Reducing hypoglycemic action Primobolan for salea possible while receiving glucocorticoids, oral contraceptives, adrenaline, glucagon, thyroid hormones, thiazide diuretics, phenothiazine derivatives.

In an application Primobolan for salea with ethanol-preparations may cause lactic acidosis.

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